I have had this problem for a long time, most often occuring when extruding something ( faces, armature, vertices ), this time I menaged to capture it in submitted blend file.
The thing is, after cancelling extrusion with right click I experience severe slowdown of CPU that persists for a long time and causes crashes. In submitted example it happened when extruding single vertex with skin modifier. I noticed that every incomplete extrusion causes this vertex to duplicate in exponential way at its coordinate - merging vertices by distance later results in removing from 17 to 170 vertices ! To reproduce this simply extrude vertex from my file, right click to cancel, and clean up mesh merging by distance. It happens despite of auto-merge vertices turned on.
What can be the cause of it ? I suspect there is something wrong with my project setup ? I never encountered similar problem in the internet, yet it happens to me almost every day
Blend file in the comment below. Using 2.92