You could play a MP3 file using the aud module
import aud
import time
sound = aud.Factory.file(pathToMP3 )
device = aud.device()
handle = device.play(sound)
# omit this to play full sound file
time.sleep(5)
handle.stop()
Alternatively you could launch any external application as described here: Run an external application with the bgeRun an external application with the bge