If the file is a .blend you can use an application handler

import bpy
from bpy.app.handlers import persistent


@persistent
def load_handler(dummy):
    print("Load Handler:", bpy.data.filepath)

bpy.app.handlers.load_post.append(load_handler)

For other file types there is no callback provided, you could iterate over all text files

for t in bpy.data.texts:
    'check for previously created' -> exec if new and add to list.

and check for new entries triggered by a timer.

Related:

• My custom timer is cancelled when loading a *.blend file
• Run an Internal script from a handler
• Is it possible to get render time per tile?

If the file is a .blend you can use an application handler

import bpy
from bpy.app.handlers import persistent


@persistent
def load_handler(dummy):
    print("Load Handler:", bpy.data.filepath)

bpy.app.handlers.load_post.append(load_handler)

For other file types there is no callback provided, you could iterate over all text files

for t in bpy.data.texts:
    'check for previously created' -> exec if new and add to list.

and check for new entries triggered by a timer.

Related:

• My custom timer is cancelled when loading a *.blend file
• Run an Internal script from a handler
• Is it possible to get render time per tile?