Do you really need all those addons? And if you do, are they really necessary all at once.

That seems neither productive nor beneficial for performance. Having many addons may eventually have a heavy toll on responsiveness and available resources.

If you really want all those addons active at once you should take advantage of workspaces.

I doubt you will need all of them simultaneously, so I'd advise creating a number of workspaces dedicated to certain tasks where you will pick a few addons you generally use in tandem relevant for that task (say modeling, animating, shading etc.).

Once created you can take advantage per workspace addon filters. In the *3D View Toolshelf*, (expand it with the <kbd>N</kbd> key) go to the *Tools* tab, *Workspace* panel, activate *Filter Addons*.

There you can pick which addons are active for that specific workspace.
[![enter image description here][1]][1]

For each task activate only the addons that seem relevant to that particular workflow.