I imagine on a material this simple, there's not going to be much of a difference. But on a complex material, it could. If you had a choice between a simple mask between two different complex shaders, or a bunch of masks between different properties of the same shader, is there an advantage?
This is not a direct answer to your question, but I think it is still relevant. I experimented a bit with the materials from your question. I made two render layers with a cube, both identical except for the material. I rendered them, used a math node set to difference to get the difference between both layers, and multiplied the result by 20000000. This was the final result:
In short, there is no visible difference between both materials.