I recently heard that it is a good idea to save the texture image not only in the textures panel...but also in a other panel as well, I think it was the uv mapping panel? Or image veiwer? And that if you didn't and closed it down then you may loose some of your work. If this sounds familiar to anyone, I was wondering why you hade to save it in essentially 2 different windows? Does Maya or 3dm have these kind of ideosyncresies also in anyone's experiance?
I think this question is about misunderstanding. Maybe someone doesnt know what your talking about or maybe you don't understand how to ask the question right? In either case...... If you save image to HDD, it will be saved. ..done. There is no reason why Blender should be deleting them.
But: If you bake, paint, texture, or edit an image in Blender, then you must save them before you close the project. Blender will don't save images when you save .blend file.