I need to be sure before buying this Wacom tablet. Is it compatible with Blender for painting, 3D modeling, and blueprinting?
I have a Wacom Intuos 4 and it works with Blender just fine, I just don't find it very helpful. It does everything that it's supposed to, but most things are easier with a mouse and keyboard.
...which is just to say that "it doesn't work very well" might mean it's not helpful, rather than that it doesn't function.
It is compatible, but it doesn't work very well. See this thread on blender.org.