I'm wondering if there is a way to sculpt some details on top of existing, already sculpted details, and then change the opacity of newly sculpted details? For example skin pores on top of a wrinkles geometry.
It's like working with layers, where you put a layer on top of the layer underneath and then set the opacity individually for each layer. This apporach is used eg. in Mudbox, please take a look at the following tutorial on 8:20 mark:
Does Blender support that approach or is there a clever way to simulate it?