Start blender from a terminal. And see if any errors show up.
How to actually execute Blender from the command line depends on the platform and where you have installed Blender. Here are basic instructions for the different platforms.
Open a terminal, then go to the directory where Blender is installed, and run Blender like this:
cd <blender installation directory>
If you have Blender installed in your PATH (usually when Blender is installed through a distribution package), you can simply run:
Open the terminal application, go to the directory where Blender is installed, and run the executable within the app bundle, with commands like this:
If you need to do this often, you can make an alias so that typing just blender in the terminal works. For that you can run a command like this in the terminal (with the appropriate path).
echo "alias blender=/Applications/Blender/blender.app/Contents/MacOS/blender" >> ~/.bash_profile
If you then open a new terminal, the following command will work:
Open the Command Prompt, go to the directory where Blender is installed, and then run Blender:
cd c:\<blender installation directory>
You can also add the Blender folder to your system PATH so that do you do not have to cd to it each time.
You can also try to reset user preferences (this will reset blender to stock)