Just started to play with smoke in Blender 2.81a, I did not use the Quick Smoke, but start from scratch.
Here are the steps I took:
- Create a sphere as Flow object
- Create a Cube as Domain (sphere is inside Domain)
- Create a Principled Volume Shader and link it to the volume of the sphere
Then press Space to run the simulation.
In Layout tab, I can see the sim only in Wireframe or Shade Mode, but not in Material Preview nor Render Mode.
In Blender 2.81a volumetrics seem to be ON by default in the Render Properties, so I don't know why I can't see it in Render Mode.