Didn't see the link untill I wrote the answer, sorry.
I'm [also] with Ray on this, it sounds like the wrong solution for the problem at hand.
If you want a smooth transition, you can animate a single UVMap with AnimAll.
Enable the builtin AnimAll addon.
Setup up the first UV position and go to the first frame, then click on Insert in the AnimAll Keyframe menu.
Move to another frame, reposition the UV map and insert another AnimAll keyframe. The animation will playback in object mode.
The created keyframes are using Blender keyframes system, even though it is not exposed for UV maps.
The keyframes are available in the Timeline, the Graph Editor and the Dopesheet.