I am now trying to do all my modeling in meter scale. The reason is that a new standard is in development called WebXR. When using this in mixed reality mode, on high end devices like Microsoft HoloLens, or Magic Leap One, as you move or rotate the scene camera also does. This camera movement is in meters.
The small default 2 x 2 x 2 cube is the size of a closet. I can scale anything down, but an object the size of your finger (scaled in meters), is really difficult to model. It can disappear with ease as you move about it.
I am using a 64 bit version of Blender 2.80. Is there some setting which makes this easier?