I have this mesh with their bones... the first (upper, called Target) bone is selected in pose mode. The bone next (down) the "Target" has IK.
as you can see the location and rotation are with cero's.
But when need to move or rotate trying to use the location and/or rotation transform... the axis are inverted...
If I modify the axis Z in location, the bone moves across the Y axis... why is that?
NOTE
That bone is not connected with others bones, to be a target bone, with the IK.