I am trying to do a simple simulation of crushing a can between a plane and a can crusher. The can crusher and planes are collision objects and the can itself has soft body physics on it. I have tried recalculating normals, adjusting inner and outer settings on the collision objects, I've messed with the order of modifiers that I put on the can, I've applied location, rotation, and scale, the objects are on the same layer etc. Also, I uploaded a gif. You notice right away that the object disappears which I couldn't figure out either. Is there something I'm missing here which is making my simulation not work?
See this answer. Looks like a similar thing is happening to your mesh. If you check the dimensions in the properties panel you'll see the values go crazy once the can disappears.
Removing the softbody modifier and re-adding a fresh one stops the disappearing act, and it doesn't look like you have any overlapping geometry. I think it's something in your softbody settings, in the Soft Body Edges section. It looks like you've tweaked that quite a bit; perhaps you've pushed it to its limits.